Share |

 

Canine Epilepsy Research Projects

 


AKC/CHF

AKC/CHF approved grants to study the molecular genetics of canine epilepsy. Dr. Gary Johnson of the University of Missouri at Columbia will receive a one-year $16,000 grant for a study titled "Molecular Genetic Basis of Epilepsy in Standard Schnauzers and English Springer Spaniels."

Dr. James Mickelson of the University of Minnesota College of Veterinary Medicine was approved for a two-year $57,000 grant for a study titled "Canine Epilepsy: Determining the Mode of Inheritance, Mapping the Genes, and Developing a Linkage Test." This is a comprehensive study that will include a number of breeds, including Vizsla and the Beagle. Johnson and Mickleson will colaborate on their study of epilepsy in the English Springer Spaniel.

 

The following abstracts appear at this URL http://www.akcchf.org/rpsummar.htm

Observation on Typing Canine Epilepsies Moving Towards Eventual Genetic Classification

Joanne Parent, D.V.M. University de Montreal

Clinical and Diagnostic Aspects of Canine Epilepsy, with Particular Reference To Differentiating Genetic And Non-Genetic Epilepsy

Dr. M. Podell; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH 43210

Standard Poodles & Canine Epilepsy . The short-term goal of the research that is presented is to identify the mode(s) of inheritance in Standard Poodles.

With help from the Dalmatian Club of America, Dalmatians have now been included in the "Reliability Study " phase of this research project. DCA has also donated funds to help with the project. B. Licht; Florida State University, Tallahassee, FL blicht@psy.fsu.edu

Statistical Evidence for a Single Gene of Large Effect on Epilepsy in the Belgian Tervuren

T. R. Famula and A. M. Oberbauer; Department of Animal Science, University of California, Davis, CA,U.S.A.

For more information on the AKC/CHF contact:
AKC Canine Health Foundation
251 W Garfield Rd, Ste 160
Aurora OH 44202
phone 330-995-0807
www.akcchf.org
all donations are tax-deductible

 

VetGen

VetGen Has been Awarded Grants from the National Institute of Health and the AKC Canine Health Foundation to Study Canine Hereditary Epilepsy for information on how to participate in this research please click on the paw

VetGen, the world's leader in veterinary genetic disease research and test development, will focus on discovering new disease genes responsible for hereditary epilepsy in dogs and humans. This research will be funded by a NIH grant entitled "Canine Gene Discovery and Epilepsy Therapy" as well as funds from the AKC Canine Health Foundation. Dr. George Brewer, VetGen's Scientific Director is the Principal Investigator. The goal is to develop a linked gene marker to one or more canine epilepsy genes. Developing such linkages is expected to lead to new gene discoveries benefiting both therapy in humans and genetic testing in dogs. VetGen will focus on collecting samples from families of Collies and Shetland Sheepdogs in which hereditary epilepsy has been documented.

Recently Beagles, Dalmatians, English Springer Spaniels Irish Setter & Vizla's have been added.

Your help is quickly needed to further this research! VetGen will focus on collecting DNA sample from families of Collies and Shetland Sheepdogs in which two or more dogs have been diagnosed with hereditary epilepsy. Informative families of other breeds are also welcome to participate in this research, because similar studies will soon follow in other breeds. To carry out the study we collect samples from affected dogs and their close relatives. Participation in all of VetGen's research is completely free and confidential. Cheek swabs are used to collect DNA samples from the inside of the dog's mouth making participation very easy.

Please call our Pedigree Collection Department at (800) 483-8436 to learn more about participating in this cutting edge canine research project. With the help of breeders, we can identify the gene(s) responsible for this disease and by appropriate breeding, greatly reduce this major health problem.


www.vetgen.com

 

 

Morris Animal Foundation

1) Karen Munana, DVM, and others are conducting a two-year study, "Evaluation of Vagal Nerve Stimulation as a Treatment for Refractory Canine Seizures", at North Carolina State University's College of Veterinary Medicine. "Stimulation of the the vagal nerve is a proven treatment for epilepsy in humans, and the investigators are evaluating the effectiveness of this treatment in dogs with poorly controlled seizures."

2) Martin J. Fettman D.V.M. Colorado State University, is initiating a 2-year study, "Dietary Effects on Phenobarbital Pharmacokinetics in Canine Epilepsy." Current treatments for epilepsy are generally directed at controlling recurrent seizures. Phenobarbital is the drug of choice for managing this condition. Differences in a dog's diet, body composition, and metabolic rate may alter the metabolism of phenobarbital. Dr. Fettman is studying these differences as they relate to optimum dosages of phenobarbital to treat epilepsy. Morris Animal Foundation is funding this canine epilepsy study with co-sponsorship support from Ivy and Ken Kail / The Moose Project.

Morris Animal Foundation
http://www.morrisanimalfoundation.org/

45 Inverness Drive East
Englewood, Colorado 80112
Toll free (800) 243-2345
(303) 790-2345

 

 

 

Breed-Specific DNA Epilepsy Research Projects (as of March 5th 1999)

 

SPORTING GROUP

Brittanys

researcher: Dr. Gary Johnson (U of MO) - vmgaryj@vetmed.missouri.edu
breed coordinator: Wendy Archinal - archinal@wadsworth.org
Pointers
researcher: Dr. Gary Johnson (U of MO) - vmgaryj@vetmed.missouri.edu
breed coordinator: Pam Waitman - pwaitman@AGFINANCE.COM
Retrievers, Golden
researcher: Dr. George Brewer (Vet Gen) -healthydog@vetgen.com
breed coordinator: (unknown)
Setters, Irish
researcher: Dr. Gary Johnson (U of MO) - vmgaryj@vetmed.missouri.edu
breed coordinator: Dr. Gary Brown - phone 510-657-6343, FAX 510-657-6855
Spaniels, English Springer
researchers: Dr. Ned Patterson (U of MN) - patte037@tc.umn.edu
& Dr. Gary Johnson (U of MO) - vmgaryj@vetmed.missouri.edu
breed coordinator: Karen Foster - georgian.kf@mindspring.com
Spaniels, Welsh Springer
researcher: Dr. Gary Johnson (U of MO) - vmgaryj@vetmed.missouri.edu
breed coordinator: Dr. Colleen M. O'Keefe - cok13@fgi.net
 
Spaniels, American Water
researcher: Dr. Gary Johnson (U of MO) - vmgaryj@vetmed.missouri.edu
breed co-ordinator : Beth Lagimoniere -rottnaws@earthlink.net
breed co-ordinator : Linda Forde- fordclaws@tfb.com
 
Vizslas
researcher: Dr. Ned Patterson (U of MN) - patte037@tc.umn.edu
breed coordinator: (not yet decided)
 
HOUND GROUP

Beagles

researcher: Dr. Ned Patterson (U of MN) - patte037@tc.umn.edu
breed coordinator: (unknown)
 
Irish Wolfhounds
researcher: several (U of PA)
breed coordinator: Anne Janis - iwstudy@earthlink.net
 

WORKING GROUP


Newfoundlands

researcher: Dr. George Brewer (VetGen) -healthydog@vetgen.com
breed coordinator: (unknown)
Rottweilers
researcher: Dr. Gary Johnson (U of MO) - vmgaryj@vetmed.missouri.edu
breed coordinator: (not yet decided)
St. Bernards
researcher: Dr. Gary Johnson (U of MO) - vmgaryj@vetmed.missouri.edu
breed coordinator: Penny Mahon - bigdog@wco.com
Standard Schnauzers
researcher: Dr. Gary Johnson (U of MO) - vmgaryj@vetmed.missouri.edu
breed coordinators: Liz Hansen -SkbkSchnzr@aol.com
Penny Duffee
Great Dane
researcher: Dr. Gary Johnson (U of MO) - vmgaryj@vetmed.missouri.edu
breed coordinator: (not yet decided)
Siberian Husky
researcher: Dr. Gary Johnson (U of MO) - vmgaryj@vetmed.missouri.edu
breed coordinator: (pending)

TERRIER GROUP - no known projects

TOY GROUP - no known projects

NON-SPORTING GROUP

Dalmatians (1)
researcher: Dr. George Brewer (VetGen) -healthydog@vetgen.com
breed cordinator: Marion Mitchell- dalcrazy@cybermesa.com
Dalmatians(2)
researcher: Dr. Gary Johnson (U of MO) - vmgaryj@vetmed.missouri.edu
breed cordinator: Marion Mitchell - dalcrazy@cybermesa.com

Poodles (Standards only at this time)
researcher: Barbara Licht (FL State U) - blicht@psy.fsu.edu
breed coordinator: (unknown)
 
Herding Group

Australian Shepherds

researcher: Dr. George Brewer (VetGen) -healthydog@vetgen.com
breed coordinator: (unknown)
Belgian Tervuren
researcher: T.R. Famula & A.M. Oberbauer (U of CA-Davis)
breed coordinator: (unknown)
Collies
researcher: Dr. George Brewer (VetGen) - healthydog@vetgen.com
breed coordinator: Barbara Schwartz - Impcolly@aol.com
Shetland Sheepdogs
researcher: Dr. George Brewer (VetGen) - healthydog@vetgen.com
breed coordinator: (unknown)
Old English Sheepdog researchers: Dr. Jerold Bell (Tufts) - geneticvet@aol.com
& Dr. Gary Johnson (U of MO) - vmgaryj@vetmed.missouri.edu
breed coordinator: Victoria Kremer - boreas@netwrx.net
 
NON-AKC / RARE BREEDS
Chinooks

researcher: Dr. Jerold Bell (Tufts) - geneticvet@aol.com
& Dr. Gary Johnson - vmgaryj@vetmed.missouri.edu
breed coordinator: Nancy Bartol -

 

Forms for submitting samples for research at the University of Missouri (Columbia)

can be downloaded at this URL http://www.canine-epilepsy.net

 

Page last update: 12/13/2011

Fund-Raising Projects for
Anti Epileptic Drug Research
and DNA Epilepsy Research

We are now taking
orders
for the 2014
EPIL-K9 Calendar!

What's Wrong With Gibson?
Children's illustrated story
book about canine epilepsy.
Percentage of proceeds will be
donated to support canine
epilepsy research. Click
graphic above to order!